Assuntos
Adenocarcinoma/secundário , Adenocarcinoma/cirurgia , Protocolos de Quimioterapia Combinada Antineoplásica/administração & dosagem , Protocolos de Quimioterapia Combinada Antineoplásica/efeitos adversos , Colo/efeitos dos fármacos , Colo/patologia , Colo/diagnóstico por imagem , Neoplasias Colorretais/patologia , Neoplasias Colorretais/terapia , Fígado Gorduroso/etiologia , Feminino , Fluoruracila/administração & dosagem , Fluoruracila/efeitos adversos , Hepatectomia , Humanos , Leucovorina/administração & dosagem , Leucovorina/efeitos adversos , Falência Hepática Aguda/etiologia , Falência Hepática Aguda/terapia , Neoplasias Hepáticas/secundário , Neoplasias Hepáticas/cirurgia , Metastasectomia , Pessoa de Meia-Idade , Terapia Neoadjuvante , Compostos Organoplatínicos/administração & dosagem , Compostos Organoplatínicos/efeitos adversos , Complicações Pós-Operatórias/terapia , Tomografia Computadorizada por Raios X , Carga TumoralRESUMO
Penile metastases are infrequent and often originate from genitor-urinary organs including bladder and prostate. In the present communication, we report an unusual case of penile metastasis from rectal adenocarcinoma. Though uncommon, this presentation is not unknown. A review of literature of penile metastases in colorectal cancers is also summarized here.
Assuntos
Adenocarcinoma/patologia , Idoso , Humanos , Masculino , Neoplasias Penianas/secundário , Neoplasias Retais/patologiaRESUMO
We report here a case of squamous cell carcinoma of Ascending colon occurring in a 58 year old male. Squamous cell carcinomas are known to occur in the Ano rectum frequently, but are extremely rare in colon especially the right colon.
Assuntos
Carcinoma de Células Escamosas/complicações , Neoplasias do Colo/complicações , Diagnóstico Diferencial , Humanos , Dor Lombar/etiologia , Masculino , Pessoa de Meia-IdadeAssuntos
Medula Óssea/patologia , Humanos , Imunoglobulina G/metabolismo , Cadeias Pesadas de Imunoglobulinas/metabolismo , Cadeias Leves de Imunoglobulina/metabolismo , Cadeias lambda de Imunoglobulina/metabolismo , Linfonodos/patologia , Linfoma de Células B/patologia , Masculino , Pessoa de Meia-Idade , Paraproteinemias/patologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/patologiaRESUMO
Chronic granulocytic leukaemia (CGL) is the commonest leukaemia among adults in India. Case records of 183 CGL patients diagnosed between 1975 and 1985 were reviewed. The median age at diagnosis was 40.5 years. Most patients presented with weakness, fullness in the left upper abdomen and fever. Splenomegaly and hepatomegaly were present in 90% and 48% respectively. Patients were treated with oral, intermittent busulphan with monitoring of total leucocyte count. Overall, 87 patients expired, including 63 (72%) due to blast crisis. The median survival was 33 months from diagnosis and 44 months from the onset of symptoms.
Assuntos
Adolescente , Adulto , Idoso , Crise Blástica/sangue , Bussulfano/efeitos adversos , Feminino , Seguimentos , Hepatomegalia/diagnóstico , Humanos , Índia , Leucemia Mielogênica Crônica BCR-ABL Positiva/sangue , Contagem de Leucócitos , Masculino , Pessoa de Meia-Idade , Esplenomegalia/diagnósticoRESUMO
Bone involvement in Chronic Granulocytic Leukemia (CGL) is rare. We describe here five such patients who presented with severe localized bone pain with involvement of femur neck, skull, tibia-upper end and spine. Lesions were osteolytic in three of them. Blast crisis was present in four of them. Survival was poor in all except one who presented in chronic phase. Bone involvement in CGL carries a poor prognosis.
Assuntos
Adulto , Crise Blástica/patologia , Doenças Ósseas/patologia , Feminino , Humanos , Leucemia Mielogênica Crônica BCR-ABL Positiva/patologia , Masculino , Pessoa de Meia-IdadeRESUMO
Five hundred and fifty two bone marrow (BM) specimens (497 aspirates, 55 biopsies) from 518 patients with nonhaematological malignancies were examined to determine the frequency of metastatic deposits. BM involvement was highest in neuroblastoma (9/14), prostate cancer (2/4), retinoblastoma (3/7), Ewing's sarcoma (14/47), rhabdomyosarcoma (5/20) and small cell carcinoma of lung (3/18). BM aspiration smears were adequate in paediatric tumours (neuroblastoma, retinoblastoma, rhabdomyosarcoma) while BM biopsies were most useful in patients with Ewing's sarcoma, prostate cancer and small cell lung cancer. We conclude that BM is an easy investigation in the diagnosis and staging of nonhaematological cancers.
Assuntos
Medula Óssea/patologia , Exame de Medula Óssea , Feminino , Humanos , Masculino , Metástase Neoplásica/patologia , Neuroblastoma/patologiaRESUMO
A 35 year old woman who was in clinical remission of acute lymphoblastic leukaemia on standard therapy presented with leukaemic involvement of both breasts. Local radiation therapy with concurrent systemic chemotherapy with vincristine, daunorubicin. L-asparaginase and prednisolone produced complete resolution of the breast lesions.
Assuntos
Adulto , Biópsia por Agulha , Medula Óssea/patologia , Mama/patologia , Neoplasias da Mama/patologia , Feminino , Humanos , Neoplasias Primárias Múltiplas/patologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/patologiaRESUMO
Granulocytic sarcoma is an uncommon tumour composed of granulocytic precursor cells. A rare presentation of granulocytic sarcoma of the ovary occurring in a patient with chronic granulocytic leukaemia in blastic crisis is reported.